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Comparing efficacy of Fractional CO2 laser and topical tacrolimus with Fractional CO2 laser and topical minoxidil in alopecia areata

Comparison of combination of Fractional CO2 laser and topical tacrolimus with combination of Fractional CO2 laser and topical minoxidil in alopecia areata- An open therapeutic trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090422
Enrollment
34
Registered
2025-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L638- Other alopecia areata

Interventions

Intervention1: Patch A - Fractional CO2 laser combined with topical tacrolimus : Simple randomisation on alopecia patches will be done for allocation of intervention. 2 patches within each individual

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with patchy pattern of alopecia areata with two or more adjacent and non contiguous patches on scalp, Above the age of 12 years Not taken any form of treatment for at least 1 month.

Exclusion criteria

Exclusion criteria: Patients with confluent scalp lesions. Patients with more than 5 patches. Patients with severe alopecia areata (alopecia universalis and totalis, ophiasis) Patients on anticoagulants Pregnancy and lactation History of hypertrophic scar or keloid Patients on any form of immunosuppressive therapy Hypersensitivity to topical tacrolimus or minoxidil application

Design outcomes

Primary

MeasureTime frame
Difference in response to treatment with combination of fractional CO2 laser and topical tacrolimus and combination of fractional CO2 laser and topical minoxidil in alopecia areata. Timepoint: 12 weeks

Secondary

MeasureTime frame
To compare the proportion of patient s satisfaction with two treatment modalities. Timepoint: 12 weeks

Countries

India

Contacts

Public ContactVijay Gandhi

University College of Medical Sciences and GTB Hospital

drvj125@gmail.com9810296835

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026