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Effectiveness of Four Calcium-Based Agents in Indirect Pulp Capping: An In Vivo Comparison

Comparative evaluation of four different calcium-based medicaments as an indirect pulp capping agent: an in vivo study - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090409
Enrollment
52
Registered
2025-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis Health Condition 2: K040- Pulpitis

Interventions

Intervention1: Indirect pulp Capping: To evaluate efficacy clinically by checking post operative pain , tenderness , neural sensibility and radiographically by checking PDL space widening , presence o

Sponsors

Dr Ray Anuja Awadhesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Tooth should be a mature permanent tooth showing a closed apex on periapical radiograph. Tooth should have carious penetration in dentin in more than half (or threequarters) the thickness of its dentin bulk as seen in periapical radiograph and diagnosed as reversible pulpitis Should have a positive response to Cold test that will confirm Neural sensibility Absence of prolonged spontaneous pain

Exclusion criteria

Exclusion criteria: Deciduous teeth .No pulpal exposure post completion of caries removal Teeth with necrosed pulp Teeth with incomplete root formation Teeth diagnosed with irreversible pulpitis with or without periapical lesion as diagnosed from radiograph Teeth affected by periodontitis Cracked tooth Teeth showing internal or external resorption Calcified canals Failure to achieve pulpal hemostasis after accidental pin point exposure of pulp Patients having systemic disease or is immunodeficient Patient in pregnancy 13.Patient on antibiotic or analgesic course within a week prior to the start of treatment

Design outcomes

Primary

MeasureTime frame
The study primarily evaluated how effectively four calcium-based materials TheraCal LC, Binar LC, CEM Cement, and Calcium Hydroxide reduced postoperative pain and preserved pulp vitality over a 6-month period following indirect pulp capping (IPC).Timepoint: 18 months

Secondary

MeasureTime frame
To evaluate efficacy of Theracal LC as IPC agent clinically by checking post operative pain , tenderness , neural sensibility and radiographically by checking PDL space widening , presence of calcific barrier and periapical radiolucency.Timepoint: 18 MONTHS

Countries

India

Contacts

Public ContactDr. NITIN KARARIA

NIMS Dental college and hospital

drnitinkararia@thedentist.name9829114149

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026