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Comparision of two irrigating Solutions to check the antimicrobial efficacy in primary Teeth

Comparative evaluation of antimicrobial efficacy of sodium hypochlorite with and without etidronic acid as root canal irrigants in primary teeth. - nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090379
Enrollment
40
Registered
2025-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: sodium hypochlorite: Sodium hypochlorite (NaOCl) is widely used irrigant in the endodontic treatment. It has antibacterial, proteolytic, dissolving and debriding properties. Interventio

Sponsors

Dr Amulya V
Lead Sponsor
sneharajn
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy children requiring endodontic treatment in primary teeth. 2. Primary teeth with at least two third of total root length remaining. 3. Presence of abscess/soft tissue swelling in relation to the involved tooth. 4. Co-operative children. 5. Spontaneous pain/ pain at night awakening the child at night.

Exclusion criteria

Exclusion criteria: 1. Medically compromised children. 2. Children with any recent antibiotic exposure in the preceding 1 months will be excluded from the study. 3. children who have used antimicrobial mouthwashes in the preceding 1 months.

Design outcomes

Primary

MeasureTime frame
microbial colonies will be counted using digital colony counter and expressed as colony forming unit (CFU) per millimetreTimepoint: 1year 6 months

Secondary

MeasureTime frame
The secondary outcome is to assess the effect of adding etidronic acid on the smear layer removal and dentin integrity during root canal irrigation. This includes evaluating any changes in the structural properties of primary tooth dentin.Timepoint: 1year 6 months

Countries

India

Contacts

Public ContactDr. Sneharaj N

The Oxford Dental College Bangalore

amulya.v685@gmail.com08748990540

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026