Comparison of effectiveness of pre operative and post operative Lornoxicam in surgical removal of mandibular third molar

Comparison of efficacy of pre-emptive and post operative lornoxicam in mandibular third molar surgeries - A split mouth study. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090367

Enrollment

Registered

2025-07-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Tablet Lornoxicam 8 mg: Tablet Lornoxicam 8 mg given one hour pre operatively. Control Intervention1: Tablet Lornoxicam 8 mg: Tablet Lornoxicam 8 mg given one hour post operatively.

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with bilaterally similar impacted mandibular third molars. 2) Patients classified under ASA I and ASA II requiring surgical extraction of bilaterally similar impacted mandibular third molars. 3) Patient willing to sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with erupted third molars. 2) Patients classified under ASA III and ASA IV. 3) Patients who have consumed any other analgesics in 24 hours before surgery. 4) Patients with gastritis and peptic ulcers. 5) Pregnant patients. 6) Patients with psychiatric illness. 7) Patients with infections like pericoronitis, pericoronal abscess, etc

Design outcomes

Primary

Measure	Time frame
1) The efficacy of Lornoxicam as a pre emptive and post operative analgesic. 2) Post operative pain 3) The number of rescue analgesics taken within 24 hours of the procedure. 4) Patient satisfaction by Likert scale.Timepoint: 1)The efficacy of Lornoxicam as a pre emptive analgesic. 2)The efficacy of Lornoxicam as a post operative analgesic. 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. 4)The number of rescue analgesics taken within 24 hours of the procedure. 5)The patient satisfaction by Likert scale on 7th follow up day.	—

Measure

Time frame

1) The efficacy of Lornoxicam as a pre emptive and post operative analgesic. 2) Post operative pain 3) The number of rescue analgesics taken within 24 hours of the procedure. 4) Patient satisfaction by Likert scale.Timepoint: 1)The efficacy of Lornoxicam as a pre emptive analgesic. 2)The efficacy of Lornoxicam as a post operative analgesic. 3)Pain at 2nd, 4th, 6th, 12th, and 24th hour post operatively using VAS. 4)The number of rescue analgesics taken within 24 hours of the procedure. 5)The patient satisfaction by Likert scale on 7th follow up day.

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Secondary

Measure	Time frame
1) The effectiveness of Lornoxicam as a pre emptive analgesic. 2) The effectiveness of Lornoxicam as a post operative analgesic. 3) Post operative pain 4) The number of rescue analgesics taken. 5) Patient satisfaction by Likert scale.Timepoint: 1)The efficacy of Lornoxicam as a pre emptive analgesic. 2)The efficacy of Lornoxicam as a post operative analgesic. 3)Pain at 2nd, 4th, 6th, 12th, & 24th hour post operatively using VAS. 4)The number of rescue analgesics taken within 24 hours of the procedure. 5)The patient satisfaction by Likert scale on 7th follow up day.	—

Measure

Time frame

1) The effectiveness of Lornoxicam as a pre emptive analgesic. 2) The effectiveness of Lornoxicam as a post operative analgesic. 3) Post operative pain 4) The number of rescue analgesics taken. 5) Patient satisfaction by Likert scale.Timepoint: 1)The efficacy of Lornoxicam as a pre emptive analgesic. 2)The efficacy of Lornoxicam as a post operative analgesic. 3)Pain at 2nd, 4th, 6th, 12th, & 24th hour post operatively using VAS. 4)The number of rescue analgesics taken within 24 hours of the procedure. 5)The patient satisfaction by Likert scale on 7th follow up day.

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Countries

India

Contacts

Public ContactDr Bhavana G Ammanagi

Raja Rajeswari dental college and hospital, Bangalore

narahari2012@yahoo.com9342519662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026