Health Condition 1: C069- Malignant neoplasm of mouth, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4: Nil: Nil
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: - Patients diagnosed with oral cancer (histopathologically confirmed) - Age between 18 to 80 years - Patients undergoing biopsy or surgical procedures from which oral cancer tissue samples can be obtained - Willing to provide informed consent for the use of their excised tissue for research purposes
Exclusion criteria
Exclusion criteria: - Patients with serious systemic illness or infections that may affect tissue integrity - Patients who have undergone chemotherapy or radiotherapy within the last 3 months - Inability or unwillingness to provide informed consent - Poor tissue quality or necrotic samples unsuitable for imaging analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development and validation of a multimodal nonlinear optical imaging system for label-free diagnosis of oral cancer tissue.Timepoint: At baseline (i.e., at the time of tissue imaging and histopathological assessment) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of machine learning model accuracy for cancer tissue classification based on imaging features.Timepoint: At baseline (i.e., immediately after image acquisition & initial model evaluation);Correlation of imaging-based findings with histopathological reports.Timepoint: At baseline (i.e., following histopathological analysis of imaged tissue samples) | — |
Countries
India
Contacts
Public ContactDr Nirmal Mazumder
Manipal Academy of Higher Education
Outcome results
None listed