Comparison of Recovery Quality with Pecs Block (Opioid-Sparing) vs Opioid-Based Anesthesia in Breast Cancer Surgery Patients A Randomized Trial

Comparison of Quality of Recovery in opioid sparing with Pectoral nerve (Pecs) block vs opioid based anesthesia in patients undergoing Modified radical mastectomy surgery. A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090265

Enrollment

Registered

2025-07-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: opiod sparing anaesthesia: 1) Before induction: Inj. Paracetamol 15 mg/kg infusion and 2) Inj. Dexamethasone 0.1 mg/kg IV. 2) Dexmedetomidine 0.75 m

Eligibility

Inclusion criteria

Inclusion criteria: American society of anaesthesiologist (ASA) class I and class II Age group 18 to 75

Exclusion criteria

Exclusion criteria: Known metastasis with the exception axillary lymph nodes. Refusal of the patient to participate in the study History of chronic opioid use Inability to understand the use of patient controlled analgesia (PCA) device

Design outcomes

Primary

Measure	Time frame
Quality of Recovery (QoR-40) at 24 hours postoperatively: Assessed using the QoR-40 questionnaire, focusing on patient recovery qualityTimepoint: 24 hours	—

Secondary

Measure	Time frame
Opioid consumption: Total opioid consumption (measured in morphine milligram equivalents) within the first 24 hours postoperatively. 2. Pain scores: Measured using the Numeric Rating Scale (NRS) . 3. Time to oral intake: Time (in hours) from the completion of surgery to the initiation of a liquid diet. 4. Time to ambulation: Time (in hours) from the completion of surgery to when the patient can stand up and walk with assistance. 5. Postoperative nausea and vomiting (PONV): Incidence and severity of PONV within the first 24 hours postoperatively, assessed using a standardized scoring system. 6. Chronic pain at 3 months: Incidence and intensity of chronic pain, assessed using a patient-reported outcome tool (e.g., NRS or a chronic pain questionnaire). Timepoint: 24 hours and 3 months	—

Measure

Time frame

Opioid consumption: Total opioid consumption (measured in morphine milligram equivalents) within the first 24 hours postoperatively. 2. Pain scores: Measured using the Numeric Rating Scale (NRS) . 3. Time to oral intake: Time (in hours) from the completion of surgery to the initiation of a liquid diet. 4. Time to ambulation: Time (in hours) from the completion of surgery to when the patient can stand up and walk with assistance. 5. Postoperative nausea and vomiting (PONV): Incidence and severity of PONV within the first 24 hours postoperatively, assessed using a standardized scoring system. 6. Chronic pain at 3 months: Incidence and intensity of chronic pain, assessed using a patient-reported outcome tool (e.g., NRS or a chronic pain questionnaire). Timepoint: 24 hours and 3 months

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Countries

India

Contacts

Public ContactDr Chandni Sinha

AIIMS PATNA

chandni.doc@gmail.com7250333148

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026