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Lichen planus pigmentosus- To compare the efficacy between ND YAG laser Vs Intense pulse light

A COMPARATIVE STUDY ON EFFICACY OF INTENSE PULSE LIGHT THERAPY WITH ORAL PULSE STERIODS VERSUS ND YAG NEODYMIUM DOPED YTTRIUM ALUMINUM GARNET LASER WITH ORAL PULSE STEROIDS IN FACIAL LICHEN PLANUS PIGMENTOSUS - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090256
Enrollment
40
Registered
2025-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L818- Other specified disorders of pigmentation

Interventions

Intervention1: ND YAG laser with oral mini pulse with dexamethasone: ND-YAG 1064nm Q-switched ND-YAG laser : spot size 6 mm, 400mJ of energy , and frequency of 5Hz single pass is given over the lesi

Sponsors

Chengalpet Medical Colllege and Hospital Chengalpet
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex above 18 years Clinical criteria slate grey to violaceous to brown pigmentation Histopathologically proven Lichen Planus Pigmentosus Patients willing to give a written informed consent

Exclusion criteria

Exclusion criteria: Pregnant and lactating women Conditions mimicking LPP like Ashy dermatosis, Nevus of ota, macular amyloidosis, pigmented contact dermatitis, melasma Active infection Patients having photosensitivity / photosensitive dermatoses Patients who are on immunosupressants, uncontrolled diabetes, Hypertension, active tuberculosis

Design outcomes

Primary

MeasureTime frame
1. Pre and post treatment clinical pictures to look for improvement in the pigmentation 2.Dermascopic assessement will also be done pre treatment and post treatment to look for dots and globular pattern, reticular pattern, hem like pattern, pseudo-reticular pattern 3. DPASI scoring system will be done 4. SKINDEX 16- for assessment of Emotional,functional and symptom domains of the patients Interval 0 month, 6 months, 9 monthsTimepoint: 0,6,9 months FOLLOW UP

Secondary

MeasureTime frame
1. Erythema, irritation & burning sensation immediately after laser treatment 2. Post inflammatory depigmentation after completing 6 sessions of ND YAG laser or IPL therapy 3. If any patient in developing side Effects of oral steroids such as Hypertension, Diabetes & cushingoid features. Complete blood count ,Random blood glucose,blood pressure will be monitored every monthTimepoint: 1. Immediately after procedure 2. After completing every sessions of ND YAG or IPL 3. 3 months after completing all 6 sessions

Countries

India

Contacts

Public ContactDr Jayakalyani

Chengalpet medical College and hospital

dermcliniccmch@gmail.com9600772668

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026