Comparing Two Nerve Transfer Techniques to Restore Elbow Movement After Upper Arm Nerve Injury: A Randomised Study

Median Nerve Fascicle Transfer Versus Ulnar Nerve Fascicle Transfer to Biceps motor branch of Musculocutaneous nerve for Restoration of Elbow Flexion in Patients with C5 C6 C7 Brachial Plexus Root Injury: A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090228

Enrollment

Registered

2025-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G540- Brachial plexus disorders Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Median nerve fasicle transfer: A median nerve fascicle will be transferred to the motor branch of Biceps muscle (branch of Musculocutaneous nerve) for elbow flexion. Patients will be f

Eligibility

Inclusion criteria

Inclusion criteria: 1.Diagnosed with C5, C6, C7 brachial plexus injury (confirmed via clinical, electrodiagnostic, EMG, MRI/CT studies) with intact hand function. 2.Absence of complete brachial plexus avulsion. 3.Presenting to OPD between 3 to 12 months since the time of injury. 4.Willing to follow up

Exclusion criteria

Exclusion criteria: 1. Complete brachial plexus injury (C5 T1). 2.Severe comorbidities affecting nerve recovery (like diabetes, peripheral neuropathy). 3. Previous trauma affecting the donor nerves. 4. Elbow joint arthrodesis 5. Displaced/ un displaced fracture of the said upper limb 6. Prior nerve transfer surgery for elbow flexion.

Design outcomes

Primary

Measure	Time frame
elbow flexion strength and recovery of biceps muscle strengthTimepoint: at 2,4,6 months post operative	—

Secondary

Measure	Time frame
Rate of nerve growth at 2, 4 & 6th month with NCV study Electromyographic evidence of reinnervation at 2, 4 & 6th month Donor site morbidity (e.g., sensory or motor deficits in the hand). Timepoint: at 2, 4, 6 months post surgery.	—

Countries

India

Contacts

Public ContactShrimoyee Roy

All India Institute of Medical Sciences, Kalyani

gaurab.prs@aiimskalyani.edu.in9748044093

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026