Health Condition 1: E119- Type 2 diabetes mellitus without complications Health Condition 2: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Scaling and root planing: Salivary and serum glutamate levels, neuropsychological assessment and clinical parameters will be assessed at baseline and four weeks post scaling and root pl
Sponsors
Dr Rama P Munishwar
Eligibility
Inclusion criteria
Inclusion criteria: 2. Patients who have not received any periodontal treatment in previous six months. 3. Patients diagnosed with T2DM as per American Diabetes Association criteria (2019). 4. Patients with a diagnosis of generalized periodontitis as per World Workshop Classification criteria (2017).
Exclusion criteria
Exclusion criteria: 1. Smokers and alcoholics. 2. Patients with systemic diseases like hypertension, cardiovascular diseases, rheumatoid arthritis, tumours, autoimmune diseases and renal diseases. 3. Pregnant and lactating females. 4. Any other systemic disease which can alter the course of periodontal disease. 5. Patients on medications like anti-inflammatory drugs, antibiotics and anti-epileptic drugs in the past 6 months. 6. Postmenopausal women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To correlate levels of salivary & serum glutamate in individuals with generalised periodontitis and type 2 diabetes mellitusTimepoint: At baseline and four weeks after scaling and root planing | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the effect of scaling and root planing on glutamate and cognitionTimepoint: Four weeks after scaling and root planing | — |
Countries
India
Contacts
Public ContactDr Ashish S Nichani
The Oxford Dental College
Outcome results
None listed