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Evaluation of Rate of Canine Movement in Upper Arch using Platelet Rich Fibrin

Comparative Evaluation of the Effects of Injectable Platelet Rich Fibrin(i-PRF) on Rate of Maxillary Canine Retraction A Split Mouth Randomized Trial - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/090218
Enrollment
20
Registered
2025-07-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Experimental group: 3 ml injectable platelet rich fibrin (i-PRF) will be made by centrifugation of patients blood according to standard instructions. 2 ml of i-PRF will be infiltrated i

Sponsors

Dr Himanshu Kumar Sah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with Class I bimaxillary protrusion and Class II Division 1 malocclusion requiring extraction of maxillary first premolar. 2. Fully erupted permanent dentition (except third molars). 3. Patient with good oral hygiene.

Exclusion criteria

Exclusion criteria: 1. Smokers. 2. Pregnant women. 3. Patients with impacted or blocked canine. 4. Patients with systemic disease. 5. Coagulation disorders or being treated with anticoagulants. 6. Patients who had previous orthodontic treatment or had radiographic evidence of bone resorption

Design outcomes

Primary

MeasureTime frame
Rate of canine retraction will compared in the experimental group and control group.Timepoint: Rate of canine retraction will be evaluated at T0 (baseline),T1 (after 1 month) and T2 (after 2 months) intervals.

Secondary

MeasureTime frame
1. To determine and compare the three-dimensional control (transverse, sagittal and vertical) of canine and molar. 2. To determine gingival and periodontal health of canine and molar. 3. To determine the most suitable technique for clinical usage.Timepoint: The study parameter will be evaluated at T0 (baseline), T1 (after 1 month) and T2 (after 2 months).

Countries

India

Contacts

Public ContactDr Himanshu Kumar Sah

Chhattisgarh Dental College and Research Institute GE Road Sundra Rajnandgaon CG 491441

tanushamahobia@gmail.com8889679680

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026