Bone Regeneration In Extracted Sockets of patients by using Eggshell-derived Nanohydroxyapatite and type 1 collagen

Efficacy Of Eggshell-derived Nanohydroxyapatite Graft For Bone Regeneration In Extracted Sockets - Randomized Control Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090205

Enrollment

Registered

2025-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K082- Atrophy of edentulous alveolar ridge

Interventions

Intervention1: Graft: 60% Egg Shell Derived NanoHydroxyapatite with 40 % Type 1 Collagen will be placed in the extraction sockets to assess bone regeneration Control Intervention1: control: No graft w

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 20 to 60 years of age. Patients indicated for extraction of maxillary and mandibular teeth Patients willing for implants post placement of graft material in the socket

Exclusion criteria

Exclusion criteria: Patients with absolute contraindication for extraction. Patients with systemic disorders Pregnant and lactating women Patients unwilling to participate in trail Patients allergic or sensitive to graft materials V or Type I collagen.

Design outcomes

Primary

Measure	Time frame
1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessmentTimepoint: 1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessment during 1 week, 1 month , 3 months post operatively	—

Measure

Time frame

1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessmentTimepoint: 1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessment during 1 week, 1 month , 3 months post operatively

—

Secondary

Measure	Time frame
1.To assess bone formation in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite 2.To assess wound healing in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite using laundry healing index 3.To assess quality of bone formation in extracted sockets in patients grafted with egg shell derived nano hydroxyapatite during implant placementTimepoint: 1.Bone formation assessed using IOPA & CBCT at 1 month & 3rd month respectively 2. wound healing assessedt using laundry healing index during 1st week, 1st month & 3rd month 3.Quality of bone formation in grafted extracted socket during implant placement after 3 months	—

Measure

Time frame

1.To assess bone formation in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite 2.To assess wound healing in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite using laundry healing index 3.To assess quality of bone formation in extracted sockets in patients grafted with egg shell derived nano hydroxyapatite during implant placementTimepoint: 1.Bone formation assessed using IOPA & CBCT at 1 month & 3rd month respectively 2. wound healing assessedt using laundry healing index during 1st week, 1st month & 3rd month 3.Quality of bone formation in grafted extracted socket during implant placement after 3 months

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Countries

India

Contacts

Public ContactDr Poonguzhali P

Sri Ramachandra Institute of Higher Education and Research

emmanuelazariah@sriramachandra.edu.in9840226274

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026