Pain relief after surgery

EFFECTIVENESS OF TRAMADOL AND KETAMINE AS ADJUVANTS TO BUPIVACAINE FOR INCISIONAL INFILTRATION FOR POSTOPERATIVE ANALGESIA FOLLOWING MAJOR ABDOMINAL SURGERY UNDER GENERAL ANESTHESIA - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090188

Enrollment

Registered

2025-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C574- Malignant neoplasm of uterine adnexa, unspecified

Interventions

Intervention1: incisional infilteration: Duration of the study is one and a half year Control Intervention1: Tramadol and Ketamine with bupivacaine: Local Infiltration at the end of surgery Subcutane

Eligibility

Inclusion criteria

Inclusion criteria: Open abdomibal surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Uncotrolled cardio respiratory disorders Altered hepatorenal function Refusal to participate Allergic to study drugs Psychological problems long term opioid users BMI more than 30 kilogram per meter square

Design outcomes

Primary

Measure	Time frame
To Compare post operative pain score Timepoint: 0 hr, 2 hr, 4 hr, 6 hr, 12 hr, 18 hr, 24 hrs after Infiltration	—

Secondary

Measure	Time frame
To compare duration of analgesia To compare post-operative rescue analgesic requirements To compare hemodynamic To compare adverse effect Timepoint: 0 hr, 2 hr, 4 hr, 6 hr, 12 hr, 18 hr, 24 hrs after Infiltration	—

Countries

India

Contacts

Public ContactDr Darotikumari Sudhirbhai Patel

Gujarat cancer and Research institute,BJMC

rnsbaps@gmail.com9825469907

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026