To compare the effect of two different drugs as an additional agent to epidural drug on duration of pain relief after surgery in lower abdominal surgeries.

Comparison of the Effect of Dexmedetomidine and Clonidine as an Adjuvant to Epidural Levobupivacaine on Duration of Post-Operative Analgesia in Total Abdominal Hysterectomy-A Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/090145

Enrollment

Registered

2025-07-03

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N950- Postmenopausal bleeding

Interventions

Intervention1: post operative epidural analgesia: effect of dexmeditomidine at 1 microgram per kilogram dose along with epidural drug of 0.5% Levobupivacaine 15ml in epidural to check post operative a

Eligibility

Inclusion criteria

Inclusion criteria: 2. American society of anesthesiologist physicial status grade I , grade II and grade III

Exclusion criteria

Exclusion criteria: 1.Sepsis and Coagulopathy 2. Uncorrected hypovolemia 3. Elevated ICP , infection in localized site and neurological disease 4. Preexisting liver disease, renal disease , cardiac disease 5. BMI >30 kg/m^2 6. Surgeries lasting more than two hours.

Design outcomes

Primary

Measure	Time frame
To compare the duration of post operative analgesiaTimepoint: 0-24 hours	—

Secondary

Measure	Time frame
motor blockadeTimepoint: 5 mins for the first half hour followed by every 10 minutes for two hours;sensory blockadeTimepoint: every minute;modified bromage scaleTimepoint: every 5 minutes for first 15 minutes	—

Countries

India

Contacts

Public ContactMahesh kumar M

SRM medical college and research centre

aarbee79@gmail.com9677053310

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026