Health Condition 1: K769- Liver disease, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Retrospective Component: All patients (age greater than equal to 18 years) with positive HAV IgM test results from Jan 1, 2022, to Dec 31, 2024 Prospective Component: All consenting adults (age greater than equal to 18 years) with cirrhosis admitted in Gastroenterology Department between 1 July 2025, and September 30 2025 Patients with negative or unknown HAV vaccination status
Exclusion criteria
Exclusion criteria: Age less than 18 years Pregnant women Inability to provide informed consent (for seroprevalence and attitudes components) Previous documented HAV vaccination (for attitudes and intervention component only)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of complications (ALF, ACLF)Timepoint: | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall mortality and cause-specific mortality Length of hospital stay (days) ICU admission: indication, duration of stay, organ support required Interventions: need for plasma exchange, continuous renal replacement therapy (CRRT), mechanical ventilation, or liver transplantation Adverse events and secondary infectionsTimepoint: | — |
Countries
India
Contacts
Dayanand Medical College and Hospital