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Estimation and Correlation of ghrelin and TNF-alpha levels in GCF of Healthy individuals and Chronic generalized periodontitis individuals with and without obesity

Estimation and Correlation of ghrelin and TNF-alpha levels in GCF of Health and Chronic generalized periodontitis with and without obesity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/090127
Enrollment
60
Registered
2025-07-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis Health Condition 2: E669- Obesity, unspecified

Interventions

Control Intervention1: not applicable: not applicable

Sponsors

Kaustubh Ram
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.presence of at least 20 natural teeth 2.Individuals with healthy periodontium 3.Subjects with normal lipid profile having BMI values given by Asian pacific Obesity-WHO 2000 a. In non obese BMI - 18.5 to 22.9 b. In Obese BMI - 25 to 29.9

Exclusion criteria

Exclusion criteria: 1.Individuals who have received periodntal therapy in last 6 months 2.individuals with Systemic disease other than obesity 3.individuals who have history of antimicrobial and anti inflammatory therapy in the past last 6 months 4.pregnent and lactating mother 5.smokers

Design outcomes

Primary

MeasureTime frame
Levels of Ghrelin and THF-alpha in GCF in healthy, periodontitis with and without obesityTimepoint: at baseline—

Secondary

MeasureTime frame
Gingival Index, Plaque Index , BMITimepoint: at baseline—

Countries

India

Contacts

Public ContactM B Kaustubh Ram

The Oxford dental college , Bangalore

sunaina1996@gmail.com9845203336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026