Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. The subject should have at least 7 or more teeth. 2. The subjects with Deep periodontal pockets greater than or equal to 6 mm in 2 non adjacent sites (or) Clinical attachment loss (CAL) greater than or equal to 4 mm in at least 4 non adjacent teeth are included for chronic periodontitis. 3. Patients with Hb A1C greater than 8 are included for diabetes. Group A- healthy subjects with no periodontitis or systemic disease Group B- chronic periodontitis with no systemic disease Group C - diabetes without chronic periodontitis Group D - chronic periodontitis and diabetes
Exclusion criteria
Exclusion criteria: 1. Subjects with history of periodontal therapy prior to 6 months. 2. Subjects under intake of drugs such as NSAIDS, Corticosteroids, antibiotics, cytotoxic agents. 3. Subjects with systemic illness, oral lesions. 4. Subjects with any history of malignancies or radiation. 5. Subjects having viral infection or pyrexia for over past one month. 6. History of smoking or alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate cytogenic damage to gingival cells in chronic periodontitis subjects and its association with diabetes.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr V Vasanth Ayswarya
Priyadarshini Dental College & Hospital
Outcome results
None listed