Health Condition 1: F422- Mixed obsessional thoughts and acts
Conditions
Interventions
Intervention1: Tab Ondansetron: tab ondansetron 4mg-8mg will be given orally in 2 divided dose for 8 weeks
Control Intervention1: Tab Fluoxetine: only standard treatment for OCD will be given(Tab Fluo
Sponsors
SN Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patient willing to participate in the study and has given written informed consent. 2.Age group 18-60 years. 3.Patients diagnosed with Obsessive-Compulsive Disorder according to DSM-5 TR.(12) 4.Currently na ve or off any psychotropic medication for at least 6 weeks.
Exclusion criteria
Exclusion criteria: 1.Treatment resistant OCD (2 adequate SSRI trial for 12 weeks) 2.History of non response to prior trial of fluoxetine with ondansetron. 3.Patient having severe psychiatric or medical comorbidities except depression. 4.Substance use disorder except nicotine and caffeine. 5.Pregnancy or lactation. 6.Patients with history of adverse reaction to study medications. 7.Inability to provide informed consent. 8.Patient with psychotic symptoms due to other organic illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in YBOCS,MADRS,CGI-I, HAM-A ,UKU Scales Timepoint: Improvement in YBOCS,MADRS,CGI-I, HAM-A ,UKU Scales | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: | — |
Countries
India
Contacts
Public ContactNidhi Kulhar
SN Medical College Agra
Outcome results
None listed