FindTrial
Sign In

To assess the effect of lung protective ventilation versus conventional ventilation on lung function in patients undergoing laparoscopic abdominal surgery under general anaesthesia

A randomized controlled study of lung protective ventilation and conventional ventilation in patients undergoing abdominal laparoscopic surgeries under general anesthesia at SMS Medical College, Jaipur - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/089978
Enrollment
188
Registered
2025-07-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K35-K38- Diseases of appendix Health Condition 2: K80- Cholelithiasis Health Condition 3: K55-K64- Other diseases of intestines Health Condition 4: K40-K46- Hernia Health Condition 5: N832- Other and unspecified ovarian cysts Health Condition 6: K81- Cholecystitis Health Condition 7: K82- Other diseases of gallbladder Health Condition 8: C20- Malignant neoplasm of rectum Health Condition 9: N25-N29- Other disorders of kidney and ureter

Interventions

Intervention1: Nil: Nil Intervention2: Lung protective ventilation: Received tidal volume 7 ml per kg, PEEP 10 cm of H2O, regular recruitment maneuvers. Control Intervention1: Conventional ventilation

Sponsors

SMS Medical College and Hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to give written informed consent. 2.Patients 18-60 years planned for laparoscopic surgeries. 3.American Society of Anaesthesiologists (ASA) grade I and II

Exclusion criteria

Exclusion criteria: 1. Patient should not be part of any other study. 2. Pateints with the need to continue prolonged mechanical ventilation after surgery. 3. Patients with abnormal spirometry.

Design outcomes

Primary

MeasureTime frame
To assess and compare intraoperative Pulmonary Oxygenation in both groups by calculating ratio of Partial pressure of oxygenation in arterial blood (PaO2) to the fraction of inspiratory oxygen concentration (FiO2), PaO2 (mmHg), PaCO2 (mmHg), PH values intraoperatively by Arteiral Blood Gas analysisTimepoint: After induction , 30 min after pneumoperitoneum and then at the end of surgery—

Secondary

MeasureTime frame
To assess and compare change in Hemodynamics parameters in both groups.Timepoint: After induction, 15min, 30 min , then hourly, 10 min before pneumoperitoneum gets closed and then at the end of surgery.;To assess and compare lung mechanics in both groupsTimepoint: After induction, 15min, 30 min , then hourly, 10 min before pneumoperitoneum gets closed and then at the end of surgery—

Countries

India

Contacts

Public ContactDr Prachi Verma

Sawai Man Singh Medical College and Hospitals

dr.induverma@gmail.com9413622967

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026