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Comparison of Salivary biomarkers levels in obese and non-obese patients with pyorrhea

DETERMINING THE SALIVARY MMP-8 LEVELS IN OBESE & NON-OBESE SUBJECTS WITH AND WITHOUT PERIODONTITIS: A PROSPECTIVE STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/089926
Enrollment
114
Registered
2025-07-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non-surgical Periodontal therapy: Non-surgical Periodontal therapy will be performed in obese subjects with and without periodontitis and non-obese subjects with periodontitis at baseli

Sponsors

Dr Prajjwal Shahi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Non Obese Periodontitis group Subjects aged between 20 to 50 years BMI less than 24.9 kg per m2 Bleeding on Probing more than equal to 10 percent 1 to 4 mm clinical attachment loss in at least 6 teeth 4 to 5 mm periodontal pocket Subject willing to participate in study & maintain regular appointments Obese without Periodontitis group Subjects aged between 20 to 50 years Obese subjects more than equal to 30 kg per m2 No clinical attachment loss Bleeding on Probing less than 10 percent Subject willing to participate in study & maintain regular appointments Obese with Periodontitis group Subjects aged between 20 to 50 years Obese Patient more than equal 30kg per m2 1 to 4 mm clinical attachment loss in atleast 6 teeth 4 to 5 mm periodontal pocket Bleeding on Probing more than equal to 10% Subjects with good compliance

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1 All forms of Tobacco users 2 Multivitamin supplements and antibiotics within the last 3 months 3 Subjects with systemic disease 4 Pregnant and lactating females. 5 Patients with history of salivary gland diseases 6 Periodontal treatment undergone in last three months 7 Subjects not willing to participate in study & maintain regular appointments

Design outcomes

Primary

MeasureTime frame
to evaluate difference in the MMP-8 levels in obese subjects with or without periodontitis and non-obese subjects with periodontitisTimepoint: At Baseline(0)—

Secondary

MeasureTime frame
To check the change in the salivary MMP 8 levels in obese subjects with or without periodontitis & non-obese subjects with periodontitisTimepoint: at 1 month—

Countries

India

Contacts

Public ContactDr Prajjwal Shahi

Manav Rachna International institute Research and Studies

pooja.sds@mrei.ac.in9891175112

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026