Health Condition 1: I639- Cerebral infarction, unspecified
Conditions
Interventions
Intervention1: Standard Therapy+ Indivisualized Homoeopathic medicine: Homoeopathic medicines will be given to this group patients as an add-on to standard therapy. Following Individualization medicin
Sponsors
Central Council for Research in Homoeopathy
HiTech Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age group: 18 years and above. 2) Both genders. 3) Confirmed diagnosed case of Acute Ischemic Stroke (confirmation done by MRI Brain/ NCCT Head at time of enrolment of patient). 4) Stroke episode having duration of symptoms of more than 6 hours. 5) NIHSS from 5 to 20 (including moderate to severe stroke episode).
Exclusion criteria
Exclusion criteria: 1) Experienced chest discomfort for greater than 15 minutes and less than 12 hours. 2) History of structural Central Nervous System disease (tumors, masses, hemorrhage, etc.) 3) Significant closed head or facial trauma within the previous 3 months. 4) Recent (within 6 weeks) major trauma, surgery (including laser eye surgery), gastrointestinal bleeding or genital-urinary bleeding. [Serious systemic bleeding is defined as potentially life-threatening bleeding which requires immediate medical intervention] 5) Papilledema. 6) Bleeding or clotting problem or patient on blood thinners. 7) Serious Systemic Disease such as advanced/terminal cancer or severe liver or kidney failure. 8) Pregnant females. 9) Lactating mothers. 10) Patients unwilling to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be assessment of neurological deficit following stroke as measured by National Institute of Health Stroke Scale (NIHSS) assessed at baseline, 3rd, 5th, 7th, 10th and 90th day.Timepoint: Baseline, 3rd, 5th, 7th, 10th and 90th day. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of deaths reported in two groups during 10 days.Timepoint: Baseline and 10th day.;Modified Rankin scale (mRS) assessment at baseline and 90th day.Timepoint: Baseline and 90th day.;Time to reach score 8 on NIHSS scaleTimepoint: Baseline, 3rd, 5th, 7th, 10th and 90th day.;Adverse events during 10 days.Timepoint: Baseline, 3rd, 5th, 7th, 10th and 90th day.;Level of CRP, IL-6 and d-dimer.Timepoint: Baseline, 3rd, 5th, 7th, 10th and 90th day. | — |
Countries
India
Contacts
Public ContactSubhankar Mishra
Central Council for Research in Homoeopathy
Outcome results
None listed