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comparison of two local anesthesia drugs immediately after injection

Comparative evaluation of adrenaline and dexmedetomidine as adjunct with lignocaine in enhancing local anesthesia: A split-mouth crossover randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089879
Enrollment
40
Registered
2025-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Dexmedetomidine: 1mcg of dexmedetomidine/1ml of 2% lignocaine as an adjunct in local anesthesia Control Intervention1: adrenaline: 2% lignocaine 1:80,000 of adrenaline as an adjunct in

Sponsors

Dr. S Vittal sai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged between 6-14years, Children with American Society of Anesthesiologists (ASA) grade I status, Children who require multiple appointments for treatment under local anesthesia as infiltration/block bilaterally.

Exclusion criteria

Exclusion criteria: Children who are allergic to local anesthetic solution, Children with local infection, abscess and pus discharge, Children who are medically compromised and special children, Children who are not willing and whose parents declined to sign informed consent.

Design outcomes

Secondary

MeasureTime frame
NILTimepoint: NIL

Primary

MeasureTime frame
Dexmedetomidine is superior as adjunct with lignocaine compared with lignocaine and adrenaline in onset of action and depth of anesthesiaTimepoint: immediately after local anesthesia administration

Countries

India

Contacts

Public ContactDr Shrutha S P

AMEs dental college hospital and research center

shruthavinit@gmail.com9483329406

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026