Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: injection tranexamic acid: after randomization patients will recieve either ijn hydrocortisone100 mg or inj tranexamic acid 1000 mg at the time of induction and will be assessed for inc
Sponsors
RAIPUR INSTITUTE OF MEDICAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA grade I and II 2. Age between 20 to 60 years 3. Patients undergoing surgeries under general anaesthesia with tracheal intubations 4. Surgeries lasting 1 to 3 hours
Exclusion criteria
Exclusion criteria: 1. Patient refusal. 2. Patient with known allergy to drug 3. Patients with IHD, valvular heart disease. 4. Patients with history of or with risk factors for thromboembolism. 5. Patients with renal dysfunction. 6. Patients with elevated AST, ALT values. 7. Pregnant and lactating patients. 8. Patients undergoing surgeries under general anaesthesia with supraglottic airway devices. 9. Patients already taking tranexamic acid or hydrocortisone (or other steroids) for any other indication. 10. History of convulsions .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. incidence and severity of post operative sore throat Timepoint: 2 hours 4 hours 6 hours 12 hours 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| has sore throat affected your ability to eat or drinkTimepoint: 2 hours 4 hours 6 hours 12hours 24 hours | — |
Countries
India
Contacts
Public ContactDR OM PRAKASH ADITYA
RAIPUR INSTITUTE OF MEDICAL SCIENCES
Outcome results
None listed