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Blood Analysis of macrophages in Patients suffering from Oral Cancer along with histological examination.

Haematological Assessment of the presence of Tumor Associated Macrophages (TAMs) with Immunohistochemical marker and Histological Special Stain in different grades of Oral Squamous Cell Carcinoma. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089859
Enrollment
22
Registered
2025-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Blood samples of Oral Squamous Cell Carcinoma Patients: Examination of macrophages in blood samples of Patients diagnosed with Oral Squamous Cell Carcinoma Control Intervention1: Haemat

Sponsors

Dr. Hardavi Dholakia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with non-healing ulcers, ulcero proliferative growth and histopathologically diagnosed as OSCC. Patients with tobacco/smoking associated habits and with non-healing ulcero-proliferative growth in buccal mucosa of patients.

Exclusion criteria

Exclusion criteria: Patients who have already undergone surgical resection of the lesion. Biopsy specimen of patients where malignancy is not detected.

Design outcomes

Primary

MeasureTime frame
Increased macrophages in peripheral blood smearTimepoint: 20 months—

Secondary

MeasureTime frame
Tissue taking up the Perls Prussian Blue Stain suggestive of the presence of macrophages in histological specimenTimepoint: 20 months—

Countries

India

Contacts

Public ContactDr Dharmesh Vasavada

Manubhai Patel Dental College and Hospital

dharmeshvasavada@gmail.com9429534246

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026