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Anterior segment OCT for diagnosing early-onset childhood glaucoma

Evaluation of Swept Source Anterior Segment Optical Coherence Tomography (SS ASOCT) as a Non-Invasive In Office Diagnostic Modality For Early Childhood Glaucoma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089855
Enrollment
30
Registered
2025-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H408- Other glaucoma

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Medical Education Cell Postgraduate Institute of Medical Education and Research Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: CASES: 1 day - 5 years of non acquired childhood Glaucoma as per CGRN classification CONTROLS: Age matched controls with NLDO Age matched controls with emmetropic eye of strabismic patient Age matched control of normal eye of strabismic patient

Exclusion criteria

Exclusion criteria: CASES: Children with secondary Glaucoma Children with ocular trauma Children with previous history of any ocular surgery CONTROLS: Children with ocular trauma Children with previous history of any ocular surgery Children with retinal pathologies

Design outcomes

Primary

MeasureTime frame
Diagnosing Childhood Glaucoma based on the appearance of Trabecular Meshwork visibility on SS ASOCT captured in office without any sedation compared to standard examination under anesthesiaTimepoint: 8 week At the time of EUA to assess the anterior chamber parameters on ASOCT when the definitive diagnosis of glaucoma is made, and then compare it to non-glaucomatous children

Secondary

MeasureTime frame
Comparison of Anterior Chamber Angle parameters Angle opening distance AOD 250 , AOD 500, Angle Recess Area ARA 250, ARA 500Timepoint: 8 week At the time of EUA to assess the anterior chamber parameters on ASOCT when the definitive diagnosis of glaucoma is made, & then compare it to non-glaucomatous children;To study whether the ASOCT findings in glaucomatous children correlates to the phenotype of glaucomaTimepoint: 8 week At the time of EUA to assess the anterior chamber parameters on ASOCT when the definitive diagnosis of glaucoma is made, & then compare it to non-glaucomatous children

Countries

India

Contacts

Public ContactSushmita Kaushik

Postgraduate Institute of Medical Education and Research Chandigarh

yshivangi15@gmail.com8755303016

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026