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A comparison between Propofol and Etomidate which are drugs used to initiate general anesthesia effect the blood sugar levels during surgery in diabetic and non diabetic patients

A comparison of General Anesthesia Induction with Propofol versus Etomidate on blood glucose concentration in Diabetic and Non Diabetic patients during elective surgical procedure. A Randomized Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089836
Enrollment
160
Registered
2025-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E08-E13- Diabetes mellitus

Interventions

Intervention1: Blood glucose monitoring: In Diabetic and Non Diabetic Individuals undergoing elective surgery after General anesthesia induction Intervention2: Blood Glucose monitoring: Using a glucom

Sponsors

Rachel Mary Louis
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists class 1 and 2 which include Non diabetic and controlled diabetic individuals 2. Patients scheduled for elective surgeries under General Anesthesia

Exclusion criteria

Exclusion criteria: 1.Individuals with associated comorbidities like Hypertension on Alpha or Beta Blockers 2.Difficult Airway 3.Emergency and Laparoscopic Surgeries 4.Sevoflurane Induction 5.Patients on any medications that alter blood glucose levels such as steroids. 6.Patients with Psychiatric Illness 7.Patients with allergy to Study Drugs. 8.Obese patients with a Body Mass Index of more than 30 percentage

Design outcomes

Primary

MeasureTime frame
To compare the effect of induction doses of Propofol and Etomidate on Blood Glucose concentration in Diabetic and Non-Diabetic Patients during Elective Surgical ProceduresTimepoint: Blood glucose will be monitored prior to general anesthesia induction and then at 5, 15 and 30 minutes respectively.—

Secondary

MeasureTime frame
1.To assess Haemodynamic response to induction doses of Propofol and Etomidate 2.To ascertain for any correlation between blood sugar and hemodynamic parameters on Induction with Propofol and Etomidate Timepoint: Hemodynamic parameters will be monitored prior to induction and then at every 5 minutes starting from general anesthesia induction till 30 minutes.—

Countries

India

Contacts

Public ContactDr Arpana Kedlaya

St Johns Medical College Hospital

drarpanak@hotmail.com9945346123

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026