Health Condition 1: I10-I16- Hypertensive diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age more than 18 years 2. Known hypertensive disorder 3. Scheduled to undergo elective, non cardiac procedures under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Uncontrolled hypertension - SBP more than 180 mmHg or DBP more than 110 mmHg 2. Known cases of coronary artery disease or congestive heart failure, significant structural heart disease, aortic disease, pacemaker 3. Arrhythmias 4. Left ventricular ejection fraction less than 35-40% 5. Hypersenstivity to Propofol emulsion or any of its constituents 6. Extremes of BMI : less than 18 or more than 30 7. Poor ECHO window
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pre and post-induction difference in Ventriculo-arterial coupling (VAC) ratioTimepoint: T1 - Pre induction T2 - Pre intubation (post induction of anaesthesia) T3 - Post intubation (5 minutes post induction) T4 - 15 minutes post induction | — |
Secondary
| Measure | Time frame |
|---|---|
| Pre-induction vs Post-induction difference in arterial elastance (Ea), end systolic elastance (Ees), left ventricular ejection fraction, stroke volume, heart rate, cardiac index, systemic vascular resistance indexTimepoint: T1 - Pre induction T2 - Pre intubation (post induction of anaesthesia) T3 - Post intubation (5 minutes post induction) T4 - 15 minutes post induction | — |
Countries
India
Contacts
AIIMS, New Delhi