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A study to compare ultrasound-guided and transnasal sphenopalatine ganglion block for reducing pain after brain surgery in adults

Effect of ultrasound guided bilateral sphenopalatine ganglion block versus transnasal bilateral sphenopalatine ganglion block on postcraniotomy pain in adult patients undergoing supratentorial craniotomies: a prospective randomised controlled study - nil

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089807
Enrollment
72
Registered
2025-06-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ultrasound guided sphenopalatine ganglion block: The procedure will be performed by using ultrasound guidance (Sonosite Fujifilm Edge II Inc, USA). An ultrasound-visible stimulation nee

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients above 18 years of age of either gender. 2) American Society of Anaesthesiologists physical status I and II patients scheduled for elective craniotomy for supratentorial space-occupying lesions under general anesthesia 3) Pre-operative Glasgow Coma Scale 15

Exclusion criteria

Exclusion criteria: 1) Patients not giving consent. 2) Patients who are allergic to any study drug. 3) Patient with bleeding diathesis. 4) Patient with a history of facial trauma. 5) Any systemic or local infection. 6) Patients not extubated immediately after surgery 7) History of nasal trauma, nasal bleed, nasal infection, nasal deformity 8) Neurosurgeries requiring pin application

Design outcomes

Primary

MeasureTime frame
Postoperative pain will be assessed at 6, 12, 24, and 48 hours using the Numerical Rating Scale (NRS)Timepoint: Postoperatively at 6, 12, 24, and 48 hours

Secondary

MeasureTime frame
Intraoperative hemodynamic parameters (Heart rate, Systolic Blood pressure, Diastolic Blood pressure, Mean Arterial Pressure, SpO2)Timepoint: 0 minutes (baseline before incision), 15 minutes, 30 minutes, 45 minutes, 60 minutes;Total post-operative analgesic consumption in 48 hoursTimepoint: 48 hours postoperatively

Countries

India

Contacts

Public ContactDr Navneh Samagh

All India Institute of Medical Sciences, Bathinda

navnehsamagh@gmail.com8427264480

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026