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Testing the Benefits of a Herbal drug for oral care

Efficacy of liquorice-infused chitosan local drug delivery system in chronic periodontitis a randomized controlled clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089764
Enrollment
30
Registered
2025-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 2 GROUPS: 6 MONTHS Control Intervention1: NIL: NIL

Sponsors

Isvarya E S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 30 to 60 years old systemically healthy participants. Chronic periodontitis patients with at least one site with a pocket depth of more than 5mm and a CAL of 3 to 4 mm.

Exclusion criteria

Exclusion criteria: History of systemic disease. Smokers and tobacco chewers. Pregnant and lactating females. Periodontal therapy within 6 months. History of Antibiotics for the past 3 months

Design outcomes

Primary

MeasureTime frame
To develop a liquorice coated chitosan chip. To analyse the cytotoxicity, composition and drug release of liquorice coated chitosan chip. Timepoint: 0 days to 3 months—

Secondary

MeasureTime frame
To evaluate the clinical effectiveness of liquorice infused chitosan chip when used as an adjunct to SRP in patients with chronic periodontitis. Timepoint: 0 DAYS TO 3 MONTHS—

Countries

India

Contacts

Public ContactISVARYA ES

KSR Institiute of Dental Science And Research

hesthernalini78@ksridsr.edu.in09486274005

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026