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Comparing Two Dental Lasers for Reducing Bacteria and Improving Outcomes in patients requiring Root Canal Retreatment

Effectiveness of 940-nm Diode and 2780-nm Er,Cr:YSGG Lasers in Bacterial Reduction and impact on treatment Outcome for Nonsurgical Endodontic Retreatment: A Randomized Clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089721
Enrollment
45
Registered
2025-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis Health Condition 2: K046- Periapical abscess with sinus Health Condition 3: K047- Periapical abscess without sinus

Interventions

Intervention1: Conventional irrigation with 3% NaOCl and 17% EDTA followed by 940-nm diode laser disinfection: During root canal retreatment, The root canal will be irradiated with a 940-nm diode lase

Sponsors

Maulana Azad Institute of Dental Sciences, New delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Medically healthy patients aged greater than 18 years of any gender, requiring endodontic retreatment with a diagnosis of symptomatic apical periodontitis or apical abscess Single rooted teeth without abrupt curvatures or anatomical complexities Teeth that can be properly isolated with a rubber dam for aseptic treatment

Exclusion criteria

Exclusion criteria: Presence of systemic diseases or conditions that may affect wound healing or immune response Patients who have taken antibiotics or NSAIDs within three months prior to the study Teeth presenting with root resorption, root fracture or associated periodontal condition Pregnant or lactating women Teeth with insufficient crown structure, preventing effective rubber dam isolation.

Design outcomes

Primary

MeasureTime frame
Reduction in microbial count as assessed by Polymerase Chain reaction (PCR)Timepoint: Pre treatment microbial sample and Post laser irradiation microbial sample

Secondary

MeasureTime frame
Postoperative Pain reductionTimepoint: Pain levels will be assessed at 24 hours, 48 hours, and 7 days post-treatment using a visual analog scale (VAS) ;Clinical and radiographic treatment outcomeTimepoint: Clinical and radiographic evaluations will be conducted at 3, 6, and 12 months to assess periapical healing and resolution of clinical symptoms

Countries

India

Contacts

Public ContactDR SUDHA YADAV

Maulana Azad Institute of Dental Sciences New Delhi

ruchika.roongta@gmail.com09582948894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026