Health Condition 1: K045- Chronic apical periodontitis Health Condition 2: K046- Periapical abscess with sinus Health Condition 3: K047- Periapical abscess without sinus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Medically healthy patients aged greater than 18 years of any gender, requiring endodontic retreatment with a diagnosis of symptomatic apical periodontitis or apical abscess Single rooted teeth without abrupt curvatures or anatomical complexities Teeth that can be properly isolated with a rubber dam for aseptic treatment
Exclusion criteria
Exclusion criteria: Presence of systemic diseases or conditions that may affect wound healing or immune response Patients who have taken antibiotics or NSAIDs within three months prior to the study Teeth presenting with root resorption, root fracture or associated periodontal condition Pregnant or lactating women Teeth with insufficient crown structure, preventing effective rubber dam isolation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in microbial count as assessed by Polymerase Chain reaction (PCR)Timepoint: Pre treatment microbial sample and Post laser irradiation microbial sample | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pain reductionTimepoint: Pain levels will be assessed at 24 hours, 48 hours, and 7 days post-treatment using a visual analog scale (VAS) ;Clinical and radiographic treatment outcomeTimepoint: Clinical and radiographic evaluations will be conducted at 3, 6, and 12 months to assess periapical healing and resolution of clinical symptoms | — |
Countries
India
Contacts
Maulana Azad Institute of Dental Sciences New Delhi