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Correlation between dissociation due to ketamine and its anti-depressant efficacy

A study of dissociation due to ketamine and its antidepressant effect in patients of major depressive disorder - nil

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089670
Enrollment
41
Registered
2025-06-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F329- Major depressive disorder, singleepisode, unspecified

Interventions

Intervention1: intravenous Ketamine: intravenous Ketamine is administered to the patients at a dose of 0.5ml/kg over 40-50 minutes Control Intervention1: NIL: NIL

Sponsors

PDMMC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with Major depressive disorder according to DSM 5 from age 18 to 65 without any other medical, surgical or psychiatric comorbidities were enrolled in the study

Exclusion criteria

Exclusion criteria: presence of medical or surgical comorbidity

Design outcomes

Primary

MeasureTime frame
Decrease in the HDRS scores i.e decrease in the symptoms of depressionTimepoint: 0 mins and 2 hrs—

Secondary

MeasureTime frame
Dissociation due to ketamineTimepoint: 30 mins—

Countries

India

Contacts

Public ContactSuraj Deshmukh

Panjabrao deshmukh memorial medical college

avsaboo72@gmail.com9422159211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026