Comparasion of post surgical pain after spine surgery patients using ultrasound gided Modified Thoracolumbar Interfascial Planeblock with adding Dexmedetomidine to Levo-bupivacaine and without adding dexmedetomidine

Comparative evaluation of Post-operative Analgesics benefits of adding Dexmedetomidine to Levo-bupivacaine in Modified Thoracolumbar Interfascial Plane Block in patients undergoing Spine Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089661

Enrollment

Registered

2025-06-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: G64- Other disorders of peripheral nervous system

Interventions

Intervention1: ltrasound guided modified thoracolumbar interfacial plane block withbupivacaine and dexmeditomidine: in one group Ultrasound guided modified thoracolumbar interfacial plane block with b

Eligibility

Inclusion criteria

Inclusion criteria: BMI , 30 UNDERGOING ELECTIVE SPINE SURGERY INVOLVING 2 OR LESS THAN 2 SEGMENTS

Exclusion criteria

Exclusion criteria: Patient s refusal Previous spinal surgery or surgery involving more than 3 levels. Local site infection History of corticosteroid therapy , Cushing s syndrome or Addison s disease Bleeding disorders or patients on anticoagulants. Allergy to study drugs Pregnant and Lactating female

Design outcomes

Primary

Measure	Time frame
To compare the duration of post operative analgesia after modified TLIP block using dexmedetomidine with levobupivacaine versus levobupivacaine alone in patients undergoing spine surgery. Timepoint: To compare the duration of post operative analgesia after modified TLIP block using dexmedetomidine with levobupivacaine versus levobupivacaine alone in patients undergoing spine surgery with in fist 24 hours of surgery	—

Measure

Time frame

To compare the duration of post operative analgesia after modified TLIP block using dexmedetomidine with levobupivacaine versus levobupivacaine alone in patients undergoing spine surgery. Timepoint: To compare the duration of post operative analgesia after modified TLIP block using dexmedetomidine with levobupivacaine versus levobupivacaine alone in patients undergoing spine surgery with in fist 24 hours of surgery

—

Secondary

Measure	Time frame
Total postoperative analgesic requirement in first 24 hours. Timepoint: 24 hous; Intraoperative and post operative hemodynamic changes. Timepoint: 24 hous;Total postoperative analgesic requirement in first 24 hours. Postoperative pain scores (Numerical Rating Scale). Post operative sedation score (Ramsay s sedation score) Timepoint: 24 hours;Incidence of adverse events if any (eg bradycardia, hypotension , hematoma) Timepoint: 24 hours	—

Measure

Time frame

Total postoperative analgesic requirement in first 24 hours. Timepoint: 24 hous; Intraoperative and post operative hemodynamic changes. Timepoint: 24 hous;Total postoperative analgesic requirement in first 24 hours. Postoperative pain scores (Numerical Rating Scale). Post operative sedation score (Ramsay s sedation score) Timepoint: 24 hours;Incidence of adverse events if any (eg bradycardia, hypotension , hematoma) Timepoint: 24 hours

—

Countries

India

Contacts

Public ContactDr Divya Sethi

ESIC Medical College And Hospital Faridabad Haryana

divyasth@gmail.com9891230700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026