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Assessing Children s Growth Using Saliva and Tooth Development Stages

Evaluation of salivary alkaline phosphatase activity and demirjians mandibular second molar calcification stages for pubertal growth assessment and their correlation with mp3 stages using digital radiography in children aged 8-14 years - a cross-sectional study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089652
Enrollment
75
Registered
2025-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Thasleema N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children aged 8-14 years old who require an orthodontic evaluation. 2. Children exhibiting a Frankel behavior rating grade of 3-4. 3. Children with no prior orthodontic treatment that could influence skeletal or dental maturation. 4.No record of trauma or injury to the middle finger of the left-hand region.

Exclusion criteria

Exclusion criteria: 1. Children with systemic medical conditions or those taking medications that may affect growth and bone metabolism. 2. Congenitally missing permanent second molars. 3. Children whose parents are unwilling to provide consent.

Design outcomes

Primary

MeasureTime frame
Relationship between Dental calcification stages, Alkaline phosphatase levels and skeletal maturityTimepoint: 2 years—

Secondary

MeasureTime frame
1. Reliability of salivary alkaline phosphatase activity in assessing skeletal maturity 2. Accuracy of Demirjian s mandibular second molar calcification stages in assessing skeletal maturity. Timepoint: 2 years—

Countries

India

Contacts

Public ContactThasleema N

Mar Baselios Dental College

ektahkhosla@mbdc.edu.in9947564657

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026