Efficacy of Karikku kashayam(tender coconut based decoction) in atopic dermatitis

Efficacy of Karikku Kashayam against Makkipoovadi Kashayam as oral and topical therapy in Infected phase of Atopic Dermatitis in children - A Randomised Controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089624

Enrollment

Registered

2025-06-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L089- Local infection of the skin and subcutaneous tissue, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children aged 3 to 12 years with diagnostic features of Atopic dermatitis and physical signs of skin infection

Exclusion criteria

Exclusion criteria: Receipt of any antibiotics or steroids in the previous seven days 2. Children with ongoing medication for any other disease.

Design outcomes

Primary

Measure	Time frame
The primary outcome will be Skin Infection Rating Scale. Clinical success is when SIRS score is zero each for pus, crust and pain and 0/1 each for erythema and itching. Clinical failure is a SIRS score of 1 for pusTimepoint: 1,7,14,28 days	—

Secondary

Measure	Time frame
Severity Scoring of Atopic Dermatitis index (SCORAD). The minimum clinically important difference is about 8.6 points. It will be assessed on days 1, 7, 14 and 28. ? Patient Oriented Eczema Measure (POEM) score. POEM measures subjective eczema severity over the previous week and results in a score from 0 to 72, with higher scores representing more severe eczema severity. The minimum clinically important difference for POEM is about 3. As POEM it is a weekly assessment score, it will be assessed on days1, 7, 14 and 28. ? Preliminary arbitrary grading system of dosha assessment in Kushta (integumentary diseases) based on Ayurveda fundamental principles on days 1, 7 ,14 and 28. Timepoint: 1,7,14,28 days	—

Measure

Time frame

Severity Scoring of Atopic Dermatitis index (SCORAD). The minimum clinically important difference is about 8.6 points. It will be assessed on days 1, 7, 14 and 28. ? Patient Oriented Eczema Measure (POEM) score. POEM measures subjective eczema severity over the previous week and results in a score from 0 to 72, with higher scores representing more severe eczema severity. The minimum clinically important difference for POEM is about 3. As POEM it is a weekly assessment score, it will be assessed on days1, 7, 14 and 28. ? Preliminary arbitrary grading system of dosha assessment in Kushta (integumentary diseases) based on Ayurveda fundamental principles on days 1, 7 ,14 and 28. Timepoint: 1,7,14,28 days

—

Countries

India

Contacts

Public ContactDr Sreedivya

Govt Ayurveda College Pariyaram Kannur

sridivya_ram@yahoo.co.in09497292474

Outcome results