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Comparing the effects of intraoperative opioid sparing effects vs opioid free anaesthesia on post operative rescue analgesic consumption

Comparing the Effect of Intraoperative Opioid Sparing Effect of Opioid-free Anaesthesia vs Opioid Anaesthesia on post operative Rescue Analgesic consumption in cardiac surgeries: A Prospective Randomized Study - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089623
Enrollment
126
Registered
2025-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I229- Subsequent ST elevation (STEMI) myocardial infarction of unspecified site

Interventions

Intervention1: Opioid sparing anaesthesia versus opioid using conventional anaesthesia in patients undergoing off pump coronary artery bypass grafting: By monitoring overall opioid consumption and com

Sponsors

Kiranmuthrajah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. 18 years of age or older 2.Scheduled for elective cardiac surgery with general anesthesia, invasive mechanical ventilation, complete median sternotomy

Exclusion criteria

Exclusion criteria: 1. Patients were excluded in case of emergent or redo surgeries 2. Patients with history of COPD. 3. Patients with known pulmonary Hypertension 4. Patients with EF less than 40% in Echocardiography 5. Patients with significant history of smoking addiction 6. Body mass index more than 35 kg/ m2 7. Obstructive sleep apnea 8. Patient Refusal

Design outcomes

Primary

MeasureTime frame
Total dosage of rescue analgesic usage - Post extubation in ICUTimepoint: Post operative time 0 minutes / 30 minutes / 1 hour / 2 hour / 4 hour / 8 hour / 10 hour / 12 hour / 14 hour / 16 hour / 18 hour / 20 hour / 22 hour / 24 hour Post operative day 0 / 1 / 2

Secondary

MeasureTime frame
1.Time from discontinuation of inhalation anaesthetic to time of extubation 2.VAS score on POD 1 / 2 / 3 3.Hemodynamic changes 4.Duration of ICU stayTimepoint: 30mins/1hour/2hour/4hour/6hour/8hour/10hour/12hour/14hour/16hour/18hour/20hour/22hour/24hour

Countries

India

Contacts

Public ContactDr Ranjith B Karthekeyan

Sri Ramachandra Institute of Higher Education and Research

ranjithkarthekeyan@sriramachandra.edu.in9841136568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026