Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4: Nil: Nil
Sponsors
Mahamana Pandit Madan Mohan Malviya Cancer Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1 Histologically proven, newly diagnosed cases of Oral Squamous Cell Carcinoma 2 Patients between age 18-70 years. 3 Patient willing to give consent. Eligibility criteria for healthy subjects : Healthy individuals between 18-70 years, with no history of malignant, metabolic or autoimmune disorders who are willing to give consent.
Exclusion criteria
Exclusion criteria: 1 Patient not willing to give consent 2 Critically ill patient 3 Pregnant and lactating women 4 Patient with malignancies other than oral squamous cell carcinoma. 5 Patients with known autoimmune disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)The mean serum levels of CYFRA 21-1, IL-8 and MCP-1 will be measured in OSCC patients vs. healthy subjects .Timepoint: All enrolled participants will be assessed at baseline for the outcomes after sample collection of all participants. There is no follow up in the study. Sample will be collected only once and biomarkers estimated and assessed for outcome. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)The distribution of levels of CYFRA 21-1, IL-8 & MCP-1 will be assessed with AJCC PROGNOSTIC STAGE GROUPS (TNM classification) & histopathological staging 2)The distribution of levels of CYFRA 21-1, IL-8 & MCP-1 will be correlated with AJCC PROGNOSTIC STAGE GROUPS (TNM classification) & with histopathological staging. Timepoint: All enrolled participants will be assessed for the outcomes at baseline after sample processing & data compilation of all participants . No follow up will be done. | — |
Countries
India
Contacts
Public ContactPriyanka Asia
Homi Bhabha Cancer Hospital , Varanasi
Outcome results
None listed