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Changes in gene activation after long term yoga practice

Genetic Signatures in Long Term Sudarshan Kriya Yoga Practitioners: A Case-Control study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089587
Enrollment
60
Registered
2025-06-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Sudarshan Kriya Yoga (SKY) and associated Sahaj Samadhi meditation: SKY is a cyclic rhythmic breathing technique with its roots in traditional yoga. The 25 minutes process includes thre

Sponsors

Sri Sri Institute for Advanced Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Healthy Long-term SKY practitioners (more than 5 years). Regular in practice with weekly long sky practice Vegetarian, no intake of smoke or alcohol or drugs No physical or psychological illness Consenting to take part in the study and provide blood sample Participants will be considered healthy if they meet the following conditions; No history or current diagnosis of major medical or psychiatric conditions, including but not limited to: Major psychiatric disorders (e.g., schizophrenia, bipolar disorder, major depressive disorder) Neurological disorders (e.g., epilepsy, multiple sclerosis, Parkinson s disease) Cardiovascular diseases (e.g., hypertension, coronary artery disease, heart failure) Diabetes mellitus (Type 1 or Type 2) Autoimmune diseases (e.g., rheumatoid arthritis, lupus) History of stroke, traumatic brain injury, or other significant vascular injury to the brain Cancer (any active or past diagnosis) Active or recent infections (within the past 6 weeks) Parasitic infections Significant hearing impairment No ongoing medical treatment for any acute or chronic conditions Practice daily SKY with Sahaj meditation practice and long kriya at least twice per month for 5 years

Exclusion criteria

Exclusion criteria: Have acute infections or other illness Any chronic communicable disease (TB, AIDS) Not able to do SKY practice currently Other mind body intervention practice

Design outcomes

Primary

MeasureTime frame
Comprehensive transcriptome profiling of long term SKY practitioners revealing changes in gene expression using total RNA sequencingTimepoint: One time point case-control study

Secondary

MeasureTime frame
Understanding the changes in specific pathways related to immunity, inflammation, oxidative stress, apoptosis & aging Identifying how long term SKY response differs from the transcriptome signatures associated with NCDs Timepoint: One time point case-control study

Countries

India

Contacts

Public ContactVinod K M

Sri Sri Institute for Advanced Research

vinod.mony@ssiar.org8848911503

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026