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A study comparing how well silver nanoparticle dressing and traditional non-eugenol dressing help heal the gums after depigmentation treatment.

Comparing the efficacy of silver nanoparticle-infused dressing and non eugenol dressing on wound healing following gingival depigmentation:a randomised controlled clinical trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089536
Enrollment
22
Registered
2025-06-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Acticoat TM: Acticoat is Silver impregnated nano particle dressing widely used for its antimicrobial, anti-inflammatory, and wound-healing properties that Promotes wound healing via ant

Sponsors

Dr Saumya Kumari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 40 years , Presence of melanin hyperpigmentation requiring depigmentation ,Systemically healthy , Good oral hygiene , Mild to moderate gingival pigmentations, Both genders are to be included , Gingival and plaque index less than 1 , have Thick gingival biotypes ,have Keratinized gingiva greater than 2mm .

Exclusion criteria

Exclusion criteria: Smokers or tobacco users, Pregnant or lactating females, History of periodontal therapy within the last 6 months before the start of the trial, Taking any medication that could affect healing, Previous depigmentation procedures.

Design outcomes

Primary

MeasureTime frame
Silver nanoparticle dressings is expected to enhance wound healing by promoting faster epithelialization and reducing inflammation, compared to non-eugenol dressing. Also monitoring salivary FGF2 levels at different intervals post-procedure provides valuable insight into tissue regeneration dynamics. Timepoint: Follow-up at baseline,7 days, 1 month and 3 month post-operatively.

Secondary

MeasureTime frame
Highlighting the patient experience and long-term oral health outcomes associated with silver nanoparticle and non-eugenol dressings. Patient-reported outcomes such as pain, taste, and discomfort will play a crucial role in determining treatment acceptability and adherence.Timepoint: Follow-up at baseline,7 days, 1 month and 3 month post-operatively.

Countries

India

Contacts

Public ContactSaumya kumari

Santosh deemed to be university

drsauravsingh4@gmail.com9826483854

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026