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Faster and Better Numbing? Adding Dexmedetomidine to Spinal Anesthesia with Ropivacaine for Lower Body Operations

COMPARISON OF DEXMEDITOMEDINE 10 MICROGRAM AS ADJUVANT FOR INFRAUMBILICAL SURGERY IN PATIENTS RECIEVING ROPIVACAINE 0.75% HEAVY SPINAL ANAESTHESIA: A RANDOMIZED OPEN TRIAL - DREAM

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089525
Enrollment
60
Registered
2025-06-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N219- Calculus of lower urinary tract, unspecified Health Condition 2: S723- Fracture of shaft of femur Health Condition 3: S822- Fracture of shaft of tibia Health Condition 4: N433- Hydrocele, unspecified Health Condition 5: N926- Irregular menstruation, unspecified Health Condition 6: C530- Malignant neoplasm of endocervix Health Condition 7: S910- Open wound of ankle Health Condition 8: L894- Pressure ulcer of contiguous siteof back, buttock and hip Health Condition 9: I83

Interventions

Intervention1: Sub Arachnoid Block R: Participant will be administered sub arachnoid block with 3cc volume of local anaesthetic agent Ropivacaine 0.75 % Heavy Control Intervention1: Subarachnoid block

Sponsors

Department Of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) American Society of anaesthesiologists (ASA) Grade I and II. 2) Age between 18-75 years. 3) Patient of either sex. 4) Undergoing lower limb and lower abdominal surgeries (hernias, urological surgeries, lower segment caesarean section etc.)

Exclusion criteria

Exclusion criteria: Upper abdominal surgeries(incision extend above umbilicus) and cesarean sections. Pt on LMWH and heparin therapy . Pre-existing neurological conditions or surgeries which are waxing and waning in nature(eg: multiple sclerosis,poliomyelitis).

Design outcomes

Primary

MeasureTime frame
Additives like dexmedetomidine improves quality of sub arachnoid block in terms of Speed of onset of action, Level of Blockade Achieved and Duration of blockadeTimepoint: Both Sensory and Motor blockade will be assessed at 0,3,5,10,20,30,60,90,120,150,180 minutes respectively to determine Time at which T10 level achieved, Highest level achieved and Two segment regression time

Secondary

MeasureTime frame
Additives like dexmedetomidine into subarachnoid block gives better post operative analgesiaTimepoint: Pain scores will be assessed at immediately Post operative ,Before shifting Out of post operative care unit after two hours & twenty four hours later to look of need of rescue Analgesia

Countries

India

Contacts

Public ContactDr Hrishikesh Sarnobat

TNMC and BYL Nair Charitable Hospital Mumbai

rushikesh.rhs@gmail.com7385314002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026