Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Injectable platelet rich fibrin administered at 14 day interval in patients with Oral lichen planus: The test side will receive PRF injections at 14 day interval as treatment. Liquid
Sponsors
POST GRADUATE INSTITUTE OF DENTAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: Clinically symptomatic cases of oral lichen planus (According to Anderson classification Clinical oral lichen planus confirmed through histopathology in accordance with WHO criteria7. Patient who gives written consent to participate in the study.
Exclusion criteria
Exclusion criteria: Patient under the age of 18 years Histopathological signs of moderate to severe dysplasia Genital or cutaneous involvement History of topical or systemic corticosteroid therapy within three months of recruitment. patients with Hemoglobin levels less than 9 gm/dl and platelet count less than 1 lakh/dl. Patients with known haematological disease, chronic liver disease and psychiatric disorders. Smokers or chewable tobacco users. Pregnant or lactating females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Changes in size of the lesion. 2. Change in intensity of pain. Timepoint: baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks and 3 months follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| o Patient satisfaction o Number of episodes of new lesions in the follow up period. o Adverse effect of injectable PRF Timepoint: baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks and 3 months follow up | — |
Countries
India
Contacts
Public ContactDR AMBIKA GUPTA
PGIDS, ROHTAK
Outcome results
None listed