Comparision of Treatment of dark circles using Platelet rich plasma vs tranexamic acid and vitamin c

Comparative evaluation of platelet rich plasma mesotherapy with combination of tranexamic acid and vitamin c mesotherapy in the treatment of periorbital hyperpigmentation-A Randomized Clinical trial - Rct

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089509

Enrollment

Registered

2025-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere

Interventions

Intervention1: Platelet rich plasma and Tranexamic acid + Vitamin C: Group A -1ml Platelet Rich plasma mesptherapy Group B- 0.5mlTranexamic acid + 0.5 ml Vitamin C Mesotherapy over the infraorbital

Eligibility

Inclusion criteria

Inclusion criteria: Male and female patients with the complaint of periorbital hyperpigmentation

Exclusion criteria

Exclusion criteria: Patients with systemic diseases

Design outcomes

Primary

Measure	Time frame
Reduction of periorbital hyperpigmentationTimepoint: Baseline	—

Secondary

Measure	Time frame
Reduction of periorbital hyperpigmentationTimepoint: 2 months	—

Countries

India

Contacts

Public ContactManjunath Rai

AJ institute of dental science ,Manglore

drmanju08@gmail.com9343340700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026