Comparing how well three natural gels Ashwagandha flavonoid gel, Quercetin gel, and Propolis gel fight harmful mouth bacteria in people with gum disease

A Comparative Evaluation of anti-microbial efficacy of Flavonoid of Withania somnifera gel with that of Quercetin gel and Propolis gel as against red complex organisms in periodontitis patients. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089506

Enrollment

Registered

2025-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Withania somnifera gel: Withania somnifera gel will be used for treatment of Stage III, Grade-B or C chronic periodontitis patients, twice daily. Duration of treatment will be 7 days. I

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient with Stage 3 grade B or grade C chronic periodontitis. 2. Clinical attachment level less than or equal to 5 mm and probing pocket depth less than or equal to 4 mm.

Exclusion criteria

Exclusion criteria: 1. Patients with any systemic disease like diabetes that can alter the course of periodontal disease progression and treatment. 2. Past periodontal therapy within 6 months. 3. Patients on systemic antibiotics or anti-inflammatory drugs for the past 3 months. 4. Usage of any other topical gels. 5. Patients allergic to Triphala or ashwagandha. 6. Pregnant or Lactating women.

Design outcomes

Primary

Measure	Time frame
Best suitable antimicrobial dose of Withania somnifera in chronic periodontitis patients against red complex organisms.Timepoint: Assessment will be done at baseline and at 6 weeks after therapeutic intervention.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Anand Wankhede

Datta Meghe Institute of Higher Education and Research

wankhedeanand@yahoo.co.in8888071287

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026