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Effect of two different type of lasers on microbial reduction and success of root canal treatment

Impact of 940-nm Diode and 2780-nm Er,Cr:YSGG Lasers Alone and in Combination with Conventional Irrigation on Endodontic Disinfection and Treatment Outcomes in Primary Endodontic Treatment: A Randomized Clinical Trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089497
Enrollment
50
Registered
2025-06-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Conventional irrigation with 3% NaOCl and 17% EDTA, followed by 940-nm diode laser disinfection.: Root canal preparation will be performed using rotary files, with the apical preparatio

Sponsors

Maulana Azad Institute of Dental Sciences, New delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Medically healthy patients aged greater than 18 years of any gender, requiring primary endodontic treatment with a diagnosis of pulp necrosis and apical abscess or apical periodontitis 2. Teeth without abrupt curvatures or anatomical complexities. 3. Teeth that can be properly isolated with a rubber dam for aseptic treatment 4. No associated periodontal condition - mobility under physiologic limit, absence of any periodontal pocket

Exclusion criteria

Exclusion criteria: 1. Presence of systemic diseases or conditions that may affect wound healing or immune response (e.g., diabetes, autoimmune diseases). 2. Patients who have taken antibiotics or NSAIDs within three months prior to the study. 3. Teeth with insufficient crown structure, preventing effective rubber dam isolation. 4. Pregnant or lactating women. 5. associated periodontal condition, root fracture or root resorption

Design outcomes

Primary

MeasureTime frame
Bacterial reduction using Polymerase Chain Reaction (PCR) after different irrigation protocolsTimepoint: At baseline and immediately after intervention

Secondary

MeasureTime frame
Postoperative Pain AssessmentTimepoint: Pain levels will be recorded at 24 hours, 48 hours, & 7 days post-treatment using a visual analog scale (VAS).;Treatment Outcome Assessment: Based on the Clinical and radiographic criteria, treatment outcome will be evaluated and categorized as Success and failure. Timepoint: 3, 6 and 12 months

Countries

India

Contacts

Public ContactDR SUDHA YADAV

Maulana Azad Institute of Dental Sciences New Delhi

ruchika.roongta@gmail.com09582948894

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026