A study to find out how effective the homeopathic medicine Cantharis vesicatoria is in reducing urinary infection symptoms, pus cells, and bacteria in people with escherichia coli urinary tract infections

An in vitro study to evaluate the homoeopathic medicine cantharis vesicatoria in different potencies on cultured escherichia coli and its clinical verification in the management of patients with urinary tract infections

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/06/089483

Enrollment

Registered

2025-06-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N390- Urinary tract infection, site notspecified

Interventions

Intervention1: CANTHARIS VESICATORIA: In vitro Study of cantharis vesicatoria in different potencies on cultured escherichia coli is done after getting the suitable potency its clinical verification

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients presenting with signs and symptoms of UTI and having signs and symptoms similar to Cantharis with positive findings in urine -microscopy/ culture as per working case definition. 2. All socio-economic groups. 3. Females of reproductive age group.

Exclusion criteria

Exclusion criteria: 1. Patients suffering from sexually transmitted diseases like HIV, syphilis, gonorrhea etc. 2. Pregnant woman and lactating mothers. 3. Catheterized patients.

Design outcomes

Primary

Measure	Time frame
1. Invitro Title-Inhibition of bacterial growth Description- Zone of bacterial growth inhibition final-Zone of bacterial growth inhibition initial. Interval- 24 hour 2. Clinical study PRIMARY OUTCOME Evaluating SHU-A Score before and after for analysing effectiveness of cantharis in the treatment of UTI.Timepoint: After invitro study appropriate potency is obtained and cantharis with indicated potency is administered according to homoeopathic principles, Repetition will be done by following the principles of homoeopathy. Each case will be reviewed in 2week intervals and will be followed up to a period of maximum of 1 month.The bacterial colony count and pus cells of these patients before and after the treatment with Cantharis will be tested and recorded.Obtained values will be taken for analysis. INVITRO STUDY Minimum of 2 months duration for in-vitro study CLINICAL STUDY Entrollment Period: 6 Months Intervention Period: 1Month Total Study Duration:12Months	—

Measure

Time frame

1. Invitro Title-Inhibition of bacterial growth Description- Zone of bacterial growth inhibition final-Zone of bacterial growth inhibition initial. Interval- 24 hour 2. Clinical study PRIMARY OUTCOME Evaluating SHU-A Score before and after for analysing effectiveness of cantharis in the treatment of UTI.Timepoint: After invitro study appropriate potency is obtained and cantharis with indicated potency is administered according to homoeopathic principles, Repetition will be done by following the principles of homoeopathy. Each case will be reviewed in 2week intervals and will be followed up to a period of maximum of 1 month.The bacterial colony count and pus cells of these patients before and after the treatment with Cantharis will be tested and recorded.Obtained values will be taken for analysis. INVITRO STUDY Minimum of 2 months duration for in-vitro study CLINICAL STUDY Entrollment Period: 6 Months Intervention Period: 1Month Total Study Duration:12Months

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Secondary

Measure	Time frame
Changes in number of pus cells in urine before & after for analysing effectiveness of cantharis in the treatment of UTI. Timepoint: Each case will be reviewed in 2week intervals & will be followed up to a period of maximum of 1 month. so after 4 weeks the outcome is meausred ,changes before & after the treatment is noted;Changes in bacterial colony count in urine culture before & after for analysing effectiveness of cantharis in the treatment of UTI.Timepoint: Each case will be reviewed in 2week intervals & will be followed up to a period of maximum of 1 month. So after 4 weeks the outcome is measured ,changes before & after the treatment is noted	—

Measure

Time frame

Changes in number of pus cells in urine before & after for analysing effectiveness of cantharis in the treatment of UTI. Timepoint: Each case will be reviewed in 2week intervals & will be followed up to a period of maximum of 1 month. so after 4 weeks the outcome is meausred ,changes before & after the treatment is noted;Changes in bacterial colony count in urine culture before & after for analysing effectiveness of cantharis in the treatment of UTI.Timepoint: Each case will be reviewed in 2week intervals & will be followed up to a period of maximum of 1 month. So after 4 weeks the outcome is measured ,changes before & after the treatment is noted

—

Countries

India

Contacts

Public ContactDr Jomitta John

Government Homoeopathic Medical College Kozhikode

lizmyajith@gmail.com9447551747

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026