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THE ROLE OF NEUTROPHIL TO LYMPHOCYTE RATION ,PLATELET TO LYMPHOCYTE RATIO, SERUM LACTATE IN EXACERBATION OF COPD

Neutrophil to lymphocyte Ratio, Platelet to lymphocyte ratio and serum lactate as prognostic indicators in patients with acute exacerbations of chronic obstructive pulmonary disease. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/06/089470
Enrollment
114
Registered
2025-06-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J980- Diseases of bronchus, not elsewhere classified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil Intervention5: Nil: Nil Intervention6: Nil: Nil

Sponsors

Department of respiratory medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients above 18 years of age All patients who are diagnosed case of COPD

Exclusion criteria

Exclusion criteria: Patient diagnosed with Bronchial Asthma Patient Diagnosed with Bronchiectasis Patient Diagnosed with Active pulmonary Tuberculosis Patient diagnosed with Malignancy

Design outcomes

Primary

MeasureTime frame
1) To assess the prognostic value of NLR in predicting in-hospital mortality in patients with acute exacerbation of COPD 2) To assess prognostic value of PLR in predicting in-hospital mortality in patients with acute exacerbation of COPD 3) To assess the prognostic value of lactate levels in predicting in-hospital mortality in patients with acute exacerbation of COPDTimepoint: 9 months—

Secondary

MeasureTime frame
1) To analyze the association between Neutrophil to Lymphocyte Ratio (NLR) and specific clinical outcomes, such as the duration of hospital stay, need for intensive care unit (ICU) admission, & mortality in patients with acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD). 2) To analyze the association between Platelet to Lymphocyte Ratio (PLR) and secondary outcomes, including the duration of hospitalization, ICU admission, and mortality in individuals experiencing acute exacerbation of COPD. 3) To analyze the association between serum lactate levels & additional clinical parameters, such as the length of hospital stay, ICU admission, & mortality, in patients with acute exacerbation of COPD.Timepoint: 9 months—

Countries

India

Contacts

Public ContactSheetal

Kasturba Hospital And Medical College Manipal

aswini.mohapatra@manipal.edu9845297200

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026