Health Condition 1: M368- Systemic disorders of connective tissue in other diseases classified elsewhere
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Consecutive patients of both genders over 18 years of age who present to Kasturba Hospital, Manipal with suspicion of connective tissue disease and tested positive for anti-Ro 52 and/or anti-Ro 60 (SSA) antibody will be included in this study.
Exclusion criteria
Exclusion criteria: Patients who test positive for other ANAs in the absence of anti-Ro52 and anti-Ro 60 (SSA) and patients under the age of 18 years will be excluded from the study. Samples received from health care units other than Kasturba Hospital, Manipal, will not be included in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.The study findings could help clarify the role of anti-Ro antibodies as biological markers or severity markers of CTDs and the clinical disease association of anti-Ro antibodies. The findings can assist clinicians in better monitoring and management of patients with connective tissue diseases. Timepoint: 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Follow-up studies could be planned to explore the direct pathogenic mechanisms of anti-Ro52 antibodies in specific connective tissue diseases.Timepoint: 18 months | — |
Countries
India
Contacts
Kasturba Medical College, Manipal