Health Condition 1: L638- Other alopecia areata
Conditions
Interventions
Intervention1: Intralesional steroids: Patients will receive intralesional injections of triamcinolone acetonide along the border of patch (10 mg/mL scalp
5mg/mL - face), injected (0.2 to 0.3ml per inch) at 3-week intervals for a total of 12 weeks.
Control Intervention1: 2% Tofacitinib ointment: Patients will apply 2% tofacitinib ointment twice daily ap
Sponsors
Dr Manobalan
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients presenting with patch type alopecia areata involving scalp or face. 2. No prior treatment with corticosteroids, JAK inhibitors, or immunosuppressive agents within the last six months.
Exclusion criteria
Exclusion criteria: 1. Patients below 18 years of age. 2. Extensive alopecia areata (sisaipho, ophiasis, reticular, alopecia sub-totalis, alopecia totalis, alopecia universalis) 3. Scarring alopecia 4. Patients with a known allergy to corticosteroids or tofacitinib. 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in severity of alopecia areata tool (SALT) score from baseline to week 12.Timepoint: baseline to week 12 | — |
Secondary
| Measure | Time frame |
|---|---|
| trichoscopic parameters, such as number of yellow dots, black dots ana vellus hair measured from baseline to week 12. adverse events including local reactions, skin atrophy, erythema, any systemic side effects.Timepoint: baseline to week 12 | — |
Countries
India
Contacts
Public ContactDr Manobalan K
Sri Venkateshwaraa medical college hospital
Outcome results
None listed