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A study compairing the effectiveness of two types of spinal anaesthesia one using a stronger form of ropivacaine alone and the other using ropivacaine combined with fentanyl for patients undergoing transurethral surgery

A comparative study of Efficacy of intrathecal hyperbaric Ropivacaine 0.75 percentage versus hyperbaric Ropivacaine with Fentanyl injection transurethral resection surgeries A Prospective Randomized study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089362
Enrollment
60
Registered
2025-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal injection of hyperbaric Ropivacaine 2 ml 0.75 percentage with Fentanyl 10 microgram: With due approval from institutional ethical committee a randomized parallel group study

Sponsors

JLN medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Body weight 40 to 80 kg. Patients belonging to ASA (American Society of Anaesthesiologist) class-I, II, and III. Patients undergoing various transurethral resection surgeries.

Exclusion criteria

Exclusion criteria: Patient s refusal and uncooperative patients. Any known hypersensitivity or contraindication to Bupivacaine, Ropivacaine. Local pathology at the site of injection or disability limiting the performance of spinal block. History of convulsion, bleeding disorder, severe neurological deficit, thyroid disorder. Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above). Patients having a history of significant neurological, psychiatric, or neuromuscular disorders.

Design outcomes

Primary

MeasureTime frame
Duration of analgesia in the post operativeperiod.Timepoint: Pain will be assessed by vas score which will be done initially 1 hrly for 4 hr then 2 hrly for 6 hr then 6hrly for 24 hr or till patient require rescue analgesia.

Secondary

MeasureTime frame
Onset and duration of sensory block Onset and duration of motor blockTimepoint: The sensory and motor block will be evaluated every 15 seconds till the onset of both sensory and motor blockade thereafter at 1 minute interval till the highest level of sensory block and complete motor blockade (Grade 3) is achieved. After that both sensory and motor block will be evaluated every 5 minutes during first 30 min, then at every 15 minutes up to 120 min, and thereafter at 30 minutes interval till complete recovery.

Countries

India

Contacts

Public ContactDr Maina Singh

Jawahar Lal Nehru medical college

mainasingh111@gmail.com9414097045

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026