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Comparison between lignocaine nebulization with and without dexmedetomidine in patients undergoing awake fiberoptic intubation following airway block

Comparative study between lignocaine nebulization with and without dexmedetomidine in patients undergoing awake fiberoptic intubation following airway block : a randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/06/089333
Enrollment
90
Registered
2025-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine with dexmedetomidine: To determine time for intubation using 2 mcg/kg dexmedetomidine with lignocaine 2% nebulization for patients undergoing awake fiberoptic intubation foll

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients that have given written, informed consent to participate the study, American Society of Anaesthesiologist physical status 1 , patients undergoing surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: Refusal to participate study, Allergy to local anaesthetics or any of the study drugs, pregnant and lactation, contraindication to regional nerve block like bleeding disorder and infection at the site of block, emergency operation

Design outcomes

Primary

MeasureTime frame
Intubation time after adding dexmedetomidine with lignocaine nebulization as additive to airway block during awake fiberoptic intubationTimepoint: At the time from passing the fiberoptic endoscope tip through the nostril to the first reading obtained by the capnograph after endotracheal intubation

Secondary

MeasureTime frame
Cough severity score, Intubating condition, Patient comfort score, Hemodynamic changes and Complications if anyTimepoint: 16 months

Countries

India

Contacts

Public ContactDr Arpita Laha

IPGMER and SSKM Hospital

anwesha951@gmail.com8016510275

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026