Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: SUGAMMADEX: Intravenous injection SUGAMMADEX 2 mg per kg body weight will be used as agent for neuromuscular block reversal
Control Intervention1: NEOSTIGMINE: Intravenous injection Ne
Sponsors
Jutimollika Hazarika
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective abdominal surgeries under general anesthesia. 2. ASA grade 1, 2 and 3. 3. Patients who have given written and informed consent. 4. Patients with no known preexisting pulmonary infection.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery 2. ASA grade 4 and above 3. Patient with incapacity to consent 4. Anticipated difficult intubation 5. Patient with preexisting chest infection 6. Patient with severe neuromuscular disease 7. History suggestive of hypersensitivity to drugs used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the incidence of postoperative pulmonary complications after reversal with either Sugammadex or Neostigmine.Timepoint: 1.Immediate post operative period 2. 12 hours post surgery 3. 24 hours post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To note the Train-of-four recovery characteristicsTimepoint: Before and after administration of reversal agent;To assess incidence of acute postoperative complications such as haemoglobin oxygen desaturation, aspiration, postoperative nausea and vomiting (PONV), Tracheal re intubation and unexpected ICU admission.Timepoint: immediate post operative period | — |
Countries
India
Contacts
Public ContactDr Rajib Hazarika
Gauhati Medical College and Hospital
Outcome results
None listed