Health Condition 1: B351- Tinea unguium
Conditions
Interventions
Intervention1: CO2 laser followed by application of Amorolfine nail laquer: Total of 6 sittings C02 laser of the affected nail every 3 weekly followed by application of amorolfine nail laquer
Control
Sponsors
AIIMS GORAKHPUR
Eligibility
Inclusion criteria
Inclusion criteria: 1. All diagnosed patients of onychomycosis (clinically and mycologically) with age more than 12 years 2. Patients with distal subungual onychomycosis, white superficial onychomycosis, max. 40 percent of the nail surface affected. 3. Patients with mild to moderate onychomycosis (with OSI less than equal to 15) 4. Patients who are willing for CO2 lser.
Exclusion criteria
Exclusion criteria: 1. Patients having localized bacterial infection around the affected nail or concomitant nail disease that causes nail dystrophy or discoloration such as psoriasis, lichen planus and atopic dermatitis that may interfere with diagnosis and treatment. 2. Patients with history of intake of oral antifungal medication within the last 3 months or the use of topical antifungal medication within the last 2 weeks prior to the laser treatment. 3. Pregnant patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Percentage of nail achieving of CER and MCR at the end of 24 week and its comparision between the 2 group. 2. Change in OSI from baseline to 24 weeks within both the groups.Timepoint: Baseline, 18 weeks, 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparision of recurrence rate in both the group during 3 month follow up after completion of CO2 laser treatment. 2. Correlation of improvement in CER & MCR with the fungal species.Timepoint: Baseline,24 weeks, 36 weeks | — |
Countries
India
Contacts
Public ContactSHIWANGI RANA
Department of Dermatology,AIIMS
Outcome results
None listed